II. Using the information about the medicine, choose the patient who can be treated with this drug. Explain your choice.



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II. Using the information about the medicine, choose the patient who can be treated with this drug. Explain your choice.



ERYTHROMYCINE Indications: alternative to penicillin in hypersensitive patients: campylobacter enteritis, pneumonia, legionnaires’ disease, syphilis, non-gonococcal urethritis, chronic prostatitis, diphtheria and whooping cough prophylaxis: acne vulgaris and rosacea   Cautions: hepatic and renal impairment: prolongation of QT interval (ventricular tachycardia reported); pregnancy (not known to be harmful) and breast-feeding (only small amount in milk); interactions: Appendix I (erythromycin and other macrolides)   Side-effects: nausea, vomiting, abdominal discomfort, diarrhoea (antibiotic-associated colitis reported); urticaria, rashes and other allergic reactions; reversible hearing loss reported after large doses; cholestatic jaundice, cardiac effects (including chest pain and arrhythmias); Stevens-Johnson syndrome, and toxic epidermal necrolysis also reported.   Doses: by mouth, ADULT and CHILD over 8 years, 250-500 mg every 6 hours or 0.5-1 g every 12 hours; up to 4 g daily in severe infections; CHILD up to 2 years 125 mg every 6 hours, 2-8 years 250 mg every 6 hours, doses doubled for severe infections. Early syphilis, 500 mg 4 times daily for 14 days Uncomplicated genital chlamydia, non-gonococcal urethritis. 500 mg twice daily for 14 days   By intravenous infusion, ADULT and CHILD severe infections, 50 mg/kg daily by continuous infusion or in divided doses every 6 hours; mild infections (oral treatment not possible), 25 mg/kg daily; NEONATE 30-45 mg/kg daily in 3 divided doses  

Patients:

1 A 4-year-old-boy with meningitis due to pneumococcus. He is allergic to penicillin.

2 A 27-year-old woman with urinary tract infection in early pregnancy.

3 A 67-year-old man with a history of chronic bronchitis now suffering from pneumonia. The causative organism is resistant to tetracycline.

4 An 18-year-old man with left leg amputation above knee following road traffic accident.

5 A 50-year-old woman with endocarditis caused by strep. viridans.

6 A 13-year-old girl with disfiguring acne.

7 A 4-year-old boy unimmunised sibling of 2-year-old boy with whooping cough.

III. Read and translate text B. Match the specialty and its duties.

                                             Text B. Pharmacy Specialties (Part II)

A Pharmacologist is a specialist who carries out the pharmacological control and researches in the manufacture of medicines, vitamins and other medical preparations, investigates medicines’ effect (medicinal substances) on an organism. A Pharmacologist investigates and tests drugs on experimental animals.He also studies both domestic and foreign scientific and technical achievements and an advanced experience in the field of the pharmacological control. As for a Pharmacist-pharmacognost, he studies herbs, bioactive connections in their composition; he prepares vegetative medical products, and also resources of vegetative medicinal raw materials.

A Pharmacist-analyst maintains quality audit of medications in the process of their production and storage and solves a question of standardization and certification of medicinal preparations.

A lot of duties are performed by a Pharmacist-manager. He deals with handling of applications, registration of returns and claims from clients; exercises control over work of chemist's warehouses. The manager is responsible for tracing of the forged and defective medicines, maintenance and development of contacts to key clients and distributors, organization of advancement production and performance of the sales’ plan; selection, training, motivation, the organization and the control of work of a command; planning of sales and the market analysis; coordination and realization of various kinds of marketing activity, besides he keeps books (accounting).

 



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