Urethral pressure profile (sphincterometry) 


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Urethral pressure profile (sphincterometry)



Resting or stress profile of the urethra is used to determine and quantify sphincter insufficiency; however, the method cannot verify subvesical obstruction. Urethral pressure profile measurement is indicated in the assessment of stress incontinence (e.g. post-traumatic, sinus urogenitalis, myelomeningocele). In children, only thin micro-tip catheters with urethral and vesical pressure transducer should be used. A continuous withdrawal is necessary to determine the functional length of the urethra (withdrawal speed of 2-10 cm/min; faster withdrawal produces higher pressure values). At rest, the urethral profile is determined by continuous withdrawal of the measuring sensor. In the urethral stress profile, the pressure in the urethra and the pressure transmission are determined during intermittent intra-abdominal pressure rises (e.g. coughing, Valsalva's manoeuvre). After voiding to completion, the bladder should be filled up to 50% of its maximum capacity with a maximum of 100 mL.

Electromyography (EMG) of the external sphincter

EMG is the study of electrical potentials generated by the depolarization of the external sphincter. For recording, skin surface electrodes are used in children, positioned left and right from the external anal sphincter. EMG should be interpreted in the light of the patient's symptoms, physical findings and urological and urodynamic investigations.

In normal subjects, there is a gradual increase in EMG activity from the pelvic floor during bladder filling; at the onset of micturition, there is complete absence of activity.

The finding of increased EMG activity during voiding, accompanied by simultaneous detrusor pressure and flow changes, is described by the term detrusor-sphincter dyssynergia (in neuropathic bladder/sphincter dysfunction) or detrusor-sphincter dysco-ordination (in neurologically normal children). Because of the many artefacts noted and the inability to distinguish electronic 'noise' from true EMG potentials on the recording, there is no consensus about using the EMG registration.

Table 19: Urodynamics: normal values in children

 

Storage phase  
Maximum cystometric bladder capacity: Age dependent (approx. age x 30)
Residual urine: < 10 % of the bladder capacity
First desire to void: Bladder filling > 60 % of the maximum bladder capacity
Intravesical pressure: 14 cmbbO at the beginning, up to 24 стНгО at the end of
  the filling
Involuntary detrusor contraction: None
Compliance: > 25 т1_/стНгО
EMG: Stable
Micturition phase (mictiometry)  
Maximum urine flow: Age dependent
Medium urine flow: Age dependent
Micturition pressure: < 75 стЬЮ (age dependent)
EMG: Fluctuations

EMG = Electromyography

REFERENCES

Agarwal SK, McLorie GA, Grewal D, Joyner BD, Bagli DJ, Khoury AE.

Urodynamic correlates of resolution of reflux in meningomyelocele patients. J Urol 1997; 158: 580-582.

Bomalaski MD, Bloom DA.

Urodynamics and massive vesicoureteral reflux. J Urol 1997; 158: 1236-1238.

Chandra M.

Nocturnal enuresis in children. CurrOpin Pediatr 1998; 10: 167-173.

Cisternino A, Passerini Glazel G.

Bladder dysfunction in children. Scand J Urol Nephrol Suppl 1995; 173: 25-28; discussion 29.

Combs AJ, Horowitz M.

A new technique for assessing detrusor leak point pressure in patients with spina bifida. J Urol 1996; 156: 757-760.

Dahms SE, Schulz-Lampel D, Thiiroff JW.

Leitlinie zur Urodynamik in der Kinderurologie. Urologe A 1998; 37: 574-575.


Ewalt DH, Bauer SB.

Pediatric neurourology. Urol Clin North Am 1996; 23: 501-509.

Hoebeke P, Raes A, Vande Walle J, Van Laecke E.

Urodynamics in children: what and how to do it? Acta Urol Belg 1998; 66: 23-30.

Hoebeke P, Vande Walle J, Everaert K, Van Laecke E, Van Gool JD.

Assessment of lower urinary tract dysfunction in children with non- neuropathic bladder sphincter dysfunction. Eur Urol 1999; 35: 57-69.



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