ТОП 10:

UNIT 5. STUDYING PHARMACEUTICAL REFERENCES



Прочитайте и переведите слова и сочетания, которые можно встретить в лекарственных аннотациях.

1) Description: features; properties; effects

2) Indications: uses; applications

3) Composition: actives; inactives; excipients

4) Presentation: packaging; dosage forms and packs; pharmaceutical form; how supplied.

5) Dosage: directions for use; dosage instructions

6) Contraindications: restrictions on use

6) Side effects: adverse effects; undesirable effects

7) Interactions: incompatibilities

8) Overdosage: overdose; toxic effects (and their treatment)

9) Precautions: caution; warnings

10) Storage: special notes; safety data

11) Expiry date: expire; best before

Подберите каждому пункту название .

1) Each ampoule of 15 ml contains:

Pentoxifylline 300 mg.

Water for injection I.P. q.s.

2) Store at room temperature in a dry place. Do not use Kreon® after the expiry date. Keep out of reach of children.

3) Treatment of insomnia.

4) There is a possibility of local allergic reaction, especially in case of prolonged treatment.

5) TRENTAL must not be employed in patients with hypersensitivity to pentoxifylline, in the presence of severe haemorrhage or acute myocardial infarction. TRENTAL should not be administered during pregnancy.

6) Adults: 1 to 2 tablets

Children 8 to 13 years: 1 tablet

Children 3 to 8 years: ¼ – ½ tablet

Up to 3 doses may be taken in 24 hours.

7) It has been reported that STAN may prolong the prothrombin time in patients who are receiving the anticoagulant warfarin. In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported.

8) 50 cartridges of 1.7 ml each

9) An overdose may produce convulsions and/or hallucinatory delirium. Rapid-action anticonvulsants should be administered by intramuscular or intravenous injection and a stomach wash effectuated even if a time interval has elapsed.

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REFERENCE

Indomethacin

Composition:

Indomethacinum 10 g in ointment base up to 100 g.

Properties:

The ointment exhibits anti-inflammatory and antiexudative properties. Being a prostaglandin synthesis inhibitor it exercises both keratolytic and antiseptic effect. The excellent resorption of this

ointment ensures its therapeutic effect creating high tissue concentrations at the application areas.

Indications:

Acute and chronic rheumatic polyarthritis, osteoarthrosis, Behterev‘s disease, degenerative articular

diseases, discopathies, neuritis, plexitis, radiculitis, post-operative edema, contusions,

thrombophlebitis, hyperkeratolytic eczemas, herpes zoster, arthropathic psoriasis, climacteric

keratosis, etc.

Contraindications:

Drug allergy, peptic and duodenal ulcer, bronchial asthma, epilepsy, Parkinsonism, during pregnancy and breast feeding, leucopenia, haemorrhagic diathesis (thrombocytopenia and coagulopathy).

Side-effects:

Allergic reactions, thrombocytopenia, agranulocytosis. Following long term treatment, however

rarely, headache, drowsiness, depressive states, hepatitis and pancreatitis can be observed especially

in more susceptible patients.

Drug interactions:

Therapeutic effect of Indomethacin decreases, if applied concurrently with salycilates. Probenecid

suppresses renal excretion of indomethacin. The effect of Indomethacin is enhanced if applied in

combination with glucocorticoids and pyrazolon derivatives.

Precautions:

If treatment lasts longer than ten days, follow carefully the patient‘s blood picture (leucocytes,

thrombocytes). If applied in combination with antibiotics, anticoagulants or antidiabetic drugs

ensure control of proper clinical and laboratory parameters.

Dosage and application:

Rub the affected joints or skin areas a few-centimetre-long tube squeeze of Indomethacin ointment,

2–3 times a day. Total daily amount should not exceed 15 cm for adults and 7.5 cm for children.

Package:

Ointment in aluminium tubes of 40 g.

Storage:

At moderate temperature (15–30oC) in light-protected areas.

Exp.term :

2 years (two years).

Produced by :

TROYAPHARM Co







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